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Human Embryonic Stem Cells

Genea Biocells has developed the world’s largest and most varied private bank of ‘gold standard’ pluripotent human embryonic stem cells with more than 150 cell lines. Disease-specific cell lines as well as unaffected and sibling lines are available, in a variety of genetic backgrounds including variation in ethnic background, HLA and blood types. Our hESC lines meet all internationally recognized requirements for stem cell research and were derived in full compliance with international ethical and regulatory guidelines – many of our lines have been registered at the NIH stem cell registry.

Human Embryonic Stem Cells

Each batch of cells undergoes strict quality control:

DNA fingerprinting

CGH karyotyping

Pluripotency marker expression by high-content analysis Pluritest `{`send link from article`}`

Mycoplasma and sterility testing

Viability and plating efficiency after thawing

Specific tests (where applicable) e.g. confirmation of CAG repeat length in Huntington's disease cell lines

Scientists at non-profit organizations can purchase Genea Biocells cell lines for in vitro research purposes and non-commercial use based on a standard MTA. For-profit customers should contact us to discuss licensing options. Our cells are supplied as frozen stocks together with 100 ml of Genea Biocells M2 culture medium for optimal post-thaw viability. Cells can either be maintained in Genea Biocells M2 or adapted to other culture platforms.

Cell Lines

Unaffected cell lines
Cell line ID Disease Status Sex Siblingship NIH Status
GENEA001 unaffected F Approved
GENEA002 unaffected M Sibling to GENEA048 Approved
GENEA015 unaffected M Sibling to GENEA016 Approved
GENEA016 unaffected F Sibling to GENEA015 Approved
GENEA019 unaffected F Sibling to GENEA020 NA
GENEA022 unaffected M Sibling to GENEA021 & GENEA023 Submission in preparation
GENEA023 unaffected M Sibling to GENEA021 & GENEA022 Submission in preparation
GENEA025 unaffected M Submission in preparation
GENEA026 unaffected M Submission in preparation
GENEA027 unaffected F Submission in preparation
GENEA028 unaffected F Submission in preparation
GENEA029 unaffected F Submission in preparation
GENEA031 unaffected F Sibling to GENEA032 & GENEA033 Submission in preparation
GENEA042 unaffected F Sibling to GENEA043 Approved
GENEA043 unaffected M Sibling to GENEA042 Approved
GENEA047 unaffected F Approved
GENEA052 unaffected M Approved
GENEA057 unaffected F Approved
GENEA075 unaffected F Submission in preparation
GENEA076 unaffected F Submission in preparation
GENEA093 unaffected F Approved
GENEA094 unaffected F  Sibling to GENEA095 Approved
GENEA104 unaffected M Approved
Diseases with reported neural phenotype and their unaffected siblings
Cell line ID Disease Status Sex Siblingship NIH Status
GENEA017 Huntington Disease (40 CAG repeats) M Approved
GENEA018 Huntington Disease (46 CAG repeats) F Approved
GENEA019 unaffected F Sibling to GENEA020 NA
GENEA020 Huntington Disease (48 CAG repeats) F Sibling to GENEA019 NA
GENEA046 Huntington Disease (45 CAG repeats) F Approved
GENEA060 Von Hipple Lindau F Sibling to GENEA061 Approved
GENEA061 Von Hipple Lindau F Sibling to GENEA060 Approved
GENEA062 Charcot Marie Tooth Syndrome Type 1A M Sibling to GENEA063 Approved
GENEA063 Charcot Marie Tooth Syndrome Type 1A F Sibling to GENEA062 Approved
GENEA064 Charcot Marie Tooth Syndrome Type 1B M Approved
GENEA065 Infantile Neuroaxonal Dystrophy M Approved
GENEA089 Huntington Disease (approx. 41 CAG repeats) F Sibling to GENEA090 & GENEA091 Approved
GENEA090 Huntington Disease (approx. 45 CAG repeats) F Sibling to GENEA089 & GENEA091 Approved
GENEA091 Huntington Disease (approx. 40 CAG repeats) F Sibling to GENEA089 & GENEA090 Approved
GENEA021 Trisomy 21 M Sibling to GENEA022 & GENEA023 Submission in preparation
GENEA022 unaffected M Sibling to GENEA021 & GENEA023 Submission in preparation
GENEA023 unaffected M Sibling to GENEA021 & GENEA022 Submission in preparation
GENEA053 Trisomy 21 M NA
GENEA074 Autosomal Dominant Torsian Dystonia F Approved
GENEA031 unaffected F Sibling to GENEA032 & GENEA033 Submission in preparation
GENEA032 Fragile X F Sibling to GENEA031 & GENEA033 Submission in preparation
GENEA033 Fragile X F Sibling to GENEA031 & GENEA032 Submission in preparation
GENEA071 Incontinentia Pigmenti M Approved
GENEA081 Merosin Deficiency 1A F Approved
GENEA086 Tuberous Sclerosis 2 M Sibling to GENEA087 Approved
GENEA087 Tuberous Sclerosis 2 M Sibling to GENEA086 Approved
GENEA067 Myotonic Dystrophy I M Approved
GENEA058 Becker Muscular Dystrophy M Approved
GENEA100 Charcot-Marie-Tooth Syndrome 1A M Approved
GENEA101 Charcot-Marie-Tooth Syndrome 1A F Approved
Diseases with reported muscle phenotype and their unaffected siblings
Cell line ID Disease Status Sex Siblingship NIH Status
GENEA024 FSH Muscular Dystrophy and Monosomy X (Turner Syndrome) F (XO) Approved
GENEA030 Emery Dreifuss Muscular Dystrophy F Submission in preparation
GENEA049 FSH Muscular Dystrophy F Sibling to GENEA050 Approved
GENEA050 FSH Muscular Dystrophy M Sibling to GENEA049 Approved
GENEA058 Becker Muscular Dystrophy M Approved
GENEA066 Myotonic Dystrophy II M Approved
GENEA067 Myotonic Dystrophy I M Approved
GENEA078 Nemaline Myopathy 2 F Sibling to GENEA079 & GENEA080 Approved
GENEA079 Nemaline Myopathy 2 M Sibling to GENEA078 & GENEA080 Approved
GENEA080 Nemaline Myopathy 2 M Sibling to GENEA078 & GENEA079 Approved
GENEA096 FSH Muscular Dystrophy F Approved
GENEA081 Merosin Deficiency 1A F Approved
Diseases with reported cardiovascular phenotype and their unaffected siblings
Cell line ID Disease Status Sex Siblingship NIH Status
GENEA083 Loeys-Dietz Syndrome 2 F Sibling to GENEA084 Approved
GENEA084 Loeys-Dietz Syndrome 2 F Sibling to GENEA083 Approved
GENEA021 Trisomy 21 M Sibling to GENEA022 & GENEA023 Submission in preparation
GENEA022 unaffected M Sibling to GENEA021 & GENEA023 Submission in preparation
GENEA023 unaffected M Sibling to GENEA021 & GENEA022 Submission in preparation
GENEA053 Trisomy 21 M NA
GENEA066 Myotonic Dystrophy II M Approved
GENEA067 Myotonic Dystrophy I M Approved
GENEA081 Merosin Deficiency 1A F Approved
Diseases with reported eye phenotype
Cell line ID Disease Status Sex Siblingship NIH Status
GENEA069 Vitelliform Macular Dystrophy M Sibling to GENEA070 Approved
GENEA070 Vitelliform Macular Dystrophy F Sibling to GENEA069 Approved
GENEA071 Incontinentia Pigmenti M Approved
GENEA072 Juvenile Retinoschisis M Approved
GENEA085 Retinitis Pigmentosa M Approved
Chromosomal abnormalities and their unaffected siblings
Cell line ID Disease Status Sex Siblingship NIH Status
GENEA021 Trisomy 21 M Sibling to GENEA022 & GENEA023 Submission in preparation
GENEA022 unaffected M Sibling to GENEA021 & GENEA023 Submission in preparation
GENEA023 unaffected M Sibling to GENEA021 & GENEA022 Submission in preparation
GENEA048 Trisomy 5  (Isogenic Control Also Available) M Sibling to GENEA002 Approved
GENEA053 Trisomy 21 M NA
GENEA055 Trisomy 22 M NA
GENEA024 FSH Muscular Dystrophy and Monosomy X (Turner Syndrome) F (XO) Approved
GENEA095 15q11.1q11.2 F SIBLING TO GENEA094 Approved
GENEA105 Trisomy 3 F Approved
Other diseases and their unaffected siblings
Cell line ID Disease Status Sex Siblingship NIH Status
GENEA031 unaffected F Sibling to GENEA032 & GENEA033 Submission in preparation
GENEA032 Fragile X F Sibling to GENEA031 & GENEA033 Submission in preparation
GENEA033 Fragile X F Sibling to GENEA031 & GENEA032 Submission in preparation
GENEA040 Cystic Fibrosis (Homozygous ∆508del) F Approved
GENEA041 Cystic Fibrosis (Heterozygous ∆508del & G551D mutation) F Approved
GENEA059 BRCA1 M Approved
GENEA060 Von Hippel Lindau F Sibling to GENEA061 Approved
GENEA061 Von Hippel Lindau F Sibling to GENEA060 Approved
GENEA068 Wilm’s Tumor F Approved
GENEA071 Incontinentia Pigmenti M Approved
GENEA073 Alpha Thalassaemia M Approved
GENEA077 Hypochondroplasia M Approved
GENEA082 Epidermolysis Bullosa – trisomy 8 and 21 F Approved
GENEA086 Tuberous Sclerosis 2 M Sibling to GENEA087 Approved
GENEA087 Tuberous Sclerosis 2 M Sibling to GENEA086 Approved
GENEA088 Simpson Golabi Behmel M Approved
GENEA097 Multiple Hereditary Exotoses F Sibling to GENEA098 Approved
GENEA098 Multiple Hereditary Exotoses ? Sibling to GENEA097 Approved
GENEA099 Spastic Paraplegia Type IV F NA

 

Conditions of Sale

In order to comply with Genea Biocells ethical and regulatory guidelines, customers are asked to complete a short registration process. Areas of review will include:

Association with an established research or biotechnology organization

Research area our stem cells will be used for. Proposed use of stem cells must be in line with our ethical principles which prohibit (1) reproductive cloning activities; (2) the use of stem cells in any unregistered human trials; (3) the use of stem cells in any human trials without the fully informed and voluntary consent of trial participants; and (4) any use in which the risk to the health of a person is increased.

Acceptance of Genea Biocells standard terms and conditions which exclude use of Genea Biocells’ stem cells in any commercial product, for reproductive purposes and for use in humans. Licensing options for commercial or therapeutic use are available.

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